Mauve 1.3.0 reviewDownload
Mauve project is a system for efficiently constructing multiple genome alignments in the presence of large-scale evolutionary events
Mauve project is a system for efficiently constructing multiple genome alignments in the presence of large-scale evolutionary events such as rearrangement and inversion.
Multiple genome alignment provides a basis for research into comparative genomics and the study of evolutionary dynamics on a new scale. Aligning whole genomes is a fundamentally different problem than aligning short sequences.
Mauve has been developed with the idea that a multiple genome aligner should require only modest computational resources. It employs algorithmic techniques that scale well in the amount of sequence being aligned.
For example, a pair of Y. pestis genomes can be aligned in under a minute, while a group of 9 divergent Enterobacterial genomes can be aligned in a few hours.
What's New in This Release:
Mauve now incorporates rearrangement history analysis by Block-Interchange (Yancopoulos et al. 2005) and GRIMM/MGR (Bourque et al. 2002).
MUSCLE has been updated to version 3.6 and related Windows bugs have been fixed.
The Mac build includes Universal binaries for both PowerPC and Intel Macs.
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