Basic Local Alignment Search Tool 2.2.15 review

Basic Local Alignment Search Tool is in short BLAST is a set of similarity search programs designed to explore all of the available s

License: Open Software License File size: 25520K Developer: National Center for Biology Information

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Basic Local Alignment Search Tool is in short BLAST is a set of similarity search programs designed to explore all of the available sequence databases regardless of whether the query is protein or DNA.

It uses a heuristic algorithm which seeks local as opposed to global alignments, and is therefore able to detect relationships among sequences which share only isolated regions of similarity.

It can be run locally as a full executable, and can be used to run BLAST searches against private, local databases, or downloaded copies of the NCBI databases. It runs on Mac OS, Win32, LINUX, Solaris, IBM AIX, SGI, Compaq OSF, and HP- UX systems.

What's New in This Release:
BLAST now uses a 28-letter protein alphabet supporting the J (leucine or isoleucine) and O (pyrrolysine) residues.
Support has been added for incremental ASN.1 output.
Searches larger than 10kbp have been accelerated. Support has been added for BLOSUM50 and BLOSUM90 score matrices.
Headers are now correctly printed for concatenated queries.